Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975867 | 0.88 | HSD17B10 (0.39) | SIRT1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28036394 | 0.80 | ALOX5 (0.39) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL28036416 | 0.76 | PTGS2 (0.47) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL28822841 | 0.74 | HRH3 (0.34) | ALDH1A1MAPTL3MBTL1TAAR1KDM4E | |
| SCHEMBL28036417 | 0.72 | ACHE (0.46) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL27975859 | 0.70 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL28036395 | 0.68 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL3695550 | 0.66 | TAAR1 (0.61) | SIRT1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL27975579 | 0.66 | TP53 (0.43) | KMT2AMEN1MAPTTDP1FLT3 | |
| SCHEMBL27975546 | 0.66 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980248-B | 3,5-bis-substituted-4-amino thiophene-2-formaldehyde compound and preparation method thereof | ZHEJIANG UNIVERSITY (CN) | 2015-11-18 | — | — | CN | disclosed |