Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 6/20 | 0.35 |
| ▸ | MARK3 | P27448 | 8/20 | 0.33 |
| ▸ | MARK4 | Q96L34 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3519201 | 0.81 | LMNA (0.37) | CRHR1PGRMARK3MARK4 | |
| SCHEMBL28014458 | 0.79 | CRHR1 (0.37) | CRHR1PGRMARK3MARK4MEN1 | |
| SCHEMBL9470123 | 0.77 | MARK3 (0.51) | CRHR1PGRMARK3MARK4 | |
| SCHEMBL9469392 | 0.76 | PGR (0.56) | PGRMARK3MEN1KMT2A | |
| SCHEMBL9469382 | 0.75 | PGR (0.43) | PGRMARK3 | |
| SCHEMBL9981596 | 0.73 | PGR (0.57) | PGRMARK3 | |
| SCHEMBL9470463 | 0.72 | PGR (0.46) | CRHR1PGRMARK3 | |
| SCHEMBL9469711 | 0.72 | PGR (0.58) | PGRMARK3 | |
| SCHEMBL9469799 | 0.72 | PGR (0.58) | PGRMARK3MEN1KMT2A | |
| SCHEMBL1699202 | 0.72 | PGR (0.43) | PGRMARK3NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918934-A | 3-substituted pyrazoles and their use as DLK inhibitors | HOFFMANN LA ROCHE | 2015-09-16 | — | — | CN | disclosed |