SCHEMBL2803734

SCHEMBL2803734

CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 2/20 0.63
KLK5 Q9Y337 2/20 0.63
MAPT P10636 1/20 0.58
ITGB3 P05106 1/20 0.56
ITGA2B P08514 1/20 0.56
ABCB1 P08183 1/20 0.51
FOLH1 Q04609 3/20 0.50
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL356734 1.00 KLK7 (0.63) KLK7KLK5MAPTITGB3ITGA2B
SCHEMBL356995 0.97 KLK7 (0.60) KLK7KLK5MAPTITGB3ITGA2B
SCHEMBL29397834 0.97 KLK7 (0.60) KLK7KLK5MAPTITGB3ITGA2B
SCHEMBL29397799 0.97 KLK7 (0.60) KLK7KLK5MAPTITGB3ITGA2B
SCHEMBL12606016 0.96 KLK7 (0.59) KLK7KLK5MAPTITGB3ITGA2B
SCHEMBL10983363 0.96 KLK7 (0.59) KLK7KLK5MAPTITGB3ITGA2B
SCHEMBL29401353 0.96 KLK7 (0.59) KLK7KLK5MAPTITGB3ITGA2B
SCHEMBL18337922 0.92 FOLH1 (0.56) KLK7KLK5FOLH1CA1CA2
SCHEMBL9976419 0.92 FOLH1 (0.56) KLK7KLK5FOLH1CA1CA2
SCHEMBL8613001 0.89 FOLH1 (0.52) KLK7KLK5FOLH1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026085848-A1 NANO-DRUG DELIVERY SYSTEM MODIFIED WITH PHENOLIC ACID OR DIPEPTIDE FOR INCREASING ORAL ABSORBABILITY AND BIOAVAILABILITY, AND USE THEREOF 四川大学 2026-04-30 WO disclosed
US-20250213645-A1 PHARMACEUTICAL COMPOSITION FOR MODULATING IMMUNE RESPONSE L-Base Co., Ltd. (KR) 2025-07-03 US disclosed
US-20250145577-A1 STEREOCHEMICALLY ENRICHED COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS TRANSLATE BIO INC (US) 2025-05-08 US disclosed
US-20240423973-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS LERCHEN, HANS-GEORG (DE) 2024-12-26 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG L-Base Co., Ltd. (KR) 2024-06-27 US disclosed
EP-4062974-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER L BASE CO LTD (KR) 2024-05-08 EP disclosed
EP-4335452-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG L-Base Co., Ltd. (KR) 2024-03-13 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-117083074-A Pharmaceutical composition for enhancing anticancer effect of anticancer drug L 基础有限公司 2023-11-17 CN disclosed
US-20100113747-A1 Coupling of Antibody Polypeptides at the C-Terminus NOVO NORDISK A/S (DK) 2010-05-06 US disclosed
US-20100105617-A1 C-Terminal Attachment of Two Chemical Groups to Peptides NOVO NORDISK HEALTH CARE AG (CH) 2010-04-29 US disclosed
EP-2121725-A1 C-TERMINAL ATTACHMENT OF TWO CHEMICAL GROUPS TO PEPTIDES Novo Nordisk Health Care AG (CH) 2009-11-25 EP disclosed
EP-2115001-A1 COUPLING OF ANTIBODY POLYPEPTIDES AT THE C-TERMINUS Novo Nordisk A/S (DK) 2009-11-11 EP disclosed
US-20090082254-A1 Coupling of Polypeptides at the C-Terminus NOVO NORDISK A/S (DK) 2009-03-26 US disclosed
EP-1986694-A1 COUPLING OF POLYPEPTIDES AT THE C-TERMINUS Novo Nordisk A/S (DK) 2008-11-05 EP disclosed
WO-2008107260-A1 COUPLING OF ANTIBODY POLYPEPTIDES AT THE C-TERMINUS NOVO NORDISK A/S (DK) 2008-09-12 WO disclosed
WO-2008098958-A1 C-TERMINAL ATTACHMENT OF TWO CHEMICAL GROUPS TO PEPTIDES NOVO NORDISK HEALTH CARE AG (DK) 2008-08-21 WO disclosed
WO-2007093594-A1 COUPLING OF POLYPEPTIDES AT THE C-TERMINUS NOVO NORDISK HEALTH CARE AG (DK) 2007-08-23 WO disclosed
EP-0244836-B1 TRIPEPTIDE DERIVATIVES Dainippon Pharmaceutical Co., Ltd. (JP) 1993-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105617-A1 C-Terminal Attachment of Two Chemical Groups to Peptides PTMS, DNPEP, VIP KLK7 777/4885KLK5 952/4885MAPT 2816/4885
US-20250213645-A1 PHARMACEUTICAL COMPOSITION FOR MODULATING IMMUNE RESPONSE ATG7, CCL11, ATG13 KLK7 780/4885KLK5 1177/4885MAPT 415/4885
US-20090082254-A1 Coupling of Polypeptides at the C-Terminus PTMS, VIP, LNPEP KLK7 2695/4885KLK5 3402/4885MAPT 3874/4885
US-20240423973-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS PCNA, TP53, BRCA1 KLK7 2841/4885KLK5 3406/4885MAPT 4327/4885
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG ALPG, SLC11A2, SGTA KLK7 90/4885KLK5 397/4885MAPT 1532/4885
US-20100113747-A1 Coupling of Antibody Polypeptides at the C-Terminus FCGRT, FCGR3B, FCGR2A KLK7 1078/4885KLK5 2244/4885MAPT 1283/4885
US-20250145577-A1 STEREOCHEMICALLY ENRICHED COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS POLB, SNRPB2, HNRNPA2B1 KLK7 2742/4885KLK5 3873/4885MAPT 1682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.