Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 7/20 | 0.48 |
| ▸ | DRD2 | P14416 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16801801 | 0.83 | HTR2A (0.47) | KDM4ELMNAALOX15HTR1AHTR2A | |
| SCHEMBL14875491 | 0.79 | HTR2A (0.48) | KDM4ELMNAALOX15SIGMAR1HTR1A | |
| SCHEMBL27795707 | 0.77 | KDM4E (0.53) | KDM4ELMNAALOX15HTR1ADRD2 | |
| SCHEMBL27788095 | 0.77 | HTR1F (0.53) | KDM4ELMNAALOX15SIGMAR1HTR1A | |
| SCHEMBL18324770 | 0.76 | TDO2 (0.71) | KDM4ELMNAALOX15HTR1AHTR2A | |
| SCHEMBL12326386 | 0.75 | GABRP (0.56) | HTR6 | |
| SCHEMBL31001707 | 0.75 | GABRP (0.56) | HTR6 | |
| SCHEMBL760604 | 0.74 | HTR2A (0.67) | KDM4EALOX15DRD2HTR2AHSD17B10 | |
| SCHEMBL18324769 | 0.74 | MAPT (0.47) | KDM4ELMNAALOX15HTR1APOLB | |
| SCHEMBL27819451 | 0.74 | HTR1A (0.46) | SIGMAR1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889983-B | Enzyme Inhibitor Compounds | PROXIMAGEN LTD. (GB) | 2015-12-09 | — | — | CN | disclosed |