SCHEMBL2803776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2803213	0.92	NPC1 (0.40)	SPRFASNSIRT5ALDH1A1OPRM1
	SCHEMBL2800485	0.91	ALDH1A1 (0.37)	SPRFASNSIRT5ALDH1A1KMT2A
	SCHEMBL2801510	0.91	EGLN1 (0.38)	SPRFASNSIRT5ALDH1A1OPRM1
	SCHEMBL2800919	0.90	ALDH1A1 (0.38)	SPRFASNSIRT5ALDH1A1PDE4B
	SCHEMBL2800478	0.90	SIRT5 (0.46)	SPRFASNSIRT5ALDH1A1USP5
	SCHEMBL2800844	0.89	SPR (0.42)	SPRFASNSIRT5ALDH1A1F11
	SCHEMBL2801637	0.89	SIRT5 (0.41)	SPRFASNSIRT5ALDH1A1F11
	SCHEMBL2798793	0.89	SPR (0.41)	SPRFASNSIRT5ALDH1A1OPRM1
	SCHEMBL2802343	0.89	JAK2 (0.38)	SPRFASNSIRT5ALDH1A1L3MBTL1
	SCHEMBL2798787	0.89	TNF (0.36)	SPRFASNSIRT5ALDH1A1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.