Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173515 | 0.70 | DGAT1 (0.38) | MAPTALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1173693 | 0.68 | DGAT1 (0.44) | MAPTALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL23535662 | 0.66 | DGAT1 (0.35) | MAPTALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL30476277 | 0.66 | DGAT1 (0.35) | MAPTALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL18547956 | 0.64 | HTR3E (0.44) | HPGDKMT2ASMN1; SMN2TP53LMNA | |
| SCHEMBL873620 | 0.63 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDKMT2ATP53 | |
| SCHEMBL181200 | 0.60 | ALDH1A1 (0.52) | MAPTALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL29401981 | 0.60 | ALDH1A1 (0.52) | MAPTALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL18554588 | 0.60 | HSD11B1 (0.48) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17224629 | 0.60 | HSD17B14 (0.38) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097389-B | 4, 7-dihydro-pyrazolo [1,5-a ] pyrazin-6-ylamine derivatives as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA N.V. (BE) | 2015-10-14 | — | — | CN | disclosed |