Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5290793 | 0.79 | L3MBTL1 (0.54) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL759605 | 0.77 | L3MBTL1 (0.56) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8261357 | 0.77 | L3MBTL1 (0.56) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1335837 | 0.77 | L3MBTL1 (0.60) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28040517 | 0.77 | MEN1 (0.61) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2956112 | 0.76 | L3MBTL1 (0.55) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27856917 | 0.76 | L3MBTL1 (0.55) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13343071 | 0.76 | L3MBTL1 (0.54) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8760435 | 0.76 | L3MBTL1 (0.58) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2723205 | 0.75 | LMNA (0.68) | L3MBTL1ALDH1A1SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103613583-B | 1,3-substituting group-4-substituted pyrazolecarboxylic acylhydrazone and its preparation method and application | GUIZHOU UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |