Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.52 |
| ▸ | TUBB | P07437 | 2/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040081 | 0.84 | KMT2A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28040080 | 0.83 | ALOX15 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28040077 | 0.81 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31321676 | 0.79 | ALOX15 (0.65) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL25295804 | 0.79 | PDK1 (0.67) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL25296448 | 0.79 | PDK1 (0.60) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL23676962 | 0.78 | ADRB2 (0.87) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL14211605 | 0.78 | ADRB2 (0.58) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL28040076 | 0.78 | KMT2A (0.61) | ADRB2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20696534 | 0.78 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | claimed |
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | disclosed |