Styrene

Styrene

SCHEMBL28040202

C/C=C(\CC)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
AKR1C3 P42330 1/20 0.40
RECQL P46063 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PTGS2 P35354 1/20 0.38
TBXAS1 P24557 2/20 0.38
NPC1 O15118 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
GLA P06280 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
HAO1 Q9UJM8 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9725237 0.83 LMNA (0.45) ALDH1A1TSHRCYP3A4CYP2C9RECQL
Styrene SCHEMBL27551584 0.83 ALDH1A1 (0.61) ALDH1A1TSHRCYP2C9AKR1C3RECQL
Styrene SCHEMBL6262408 0.82 ALDH1A1 (0.42) ALDH1A1TSHRCYP3A4CYP2C9AKR1C3
Styrene SCHEMBL10808703 0.82 AKR1C3 (0.46) ALDH1A1TSHRCYP3A4CYP2C9AKR1C3
Styrene SCHEMBL7110641 0.81 ALOX5 (0.43) ALDH1A1TSHRCYP3A4CYP2C9RECQL
Styrene SCHEMBL27304452 0.81 ALDH1A1 (0.58) ALDH1A1TSHRCYP2C9AKR1C3RECQL
Styrene SCHEMBL4556756 0.81 ALDH1A1 (0.58) ALDH1A1TSHRCYP2C9AKR1C3RECQL
Styrene SCHEMBL238870 0.80 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4CYP2C9AKR1C3
Styrene SCHEMBL3154417 0.79 ALDH1A1 (0.56) ALDH1A1TSHRAKR1C3RECQLMEN1
Styrene SCHEMBL27501290 0.79 ALDH1A1 (0.56) ALDH1A1TSHRCYP2C9AKR1C3RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085777-B Polystyrene 2-ethyl crotonate and preparation method and application thereof 中国石油天然气股份有限公司 2017-12-05 CN disclosed
CN-105085777-A Polystyrene 2-ethyl crotonate and preparation method and application thereof PETROCHINA CO LTD 2015-11-25 CN disclosed