Styrene

Styrene

SCHEMBL9725237

C=Cc1ccccc1.CC=C(CCCC)C(=O)O

nearest known ligand 0.45

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
ALOX5 P09917 4/20 0.45
PTGES O14684 3/20 0.45
PPARG P37231 2/20 0.45
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
APEX1 P27695 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
EGFR P00533 1/20 0.38
HDAC3 O15379 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7110641 0.88 ALOX5 (0.43) LMNAALOX5PTGESPPARGTDP1
Styrene SCHEMBL27585078 0.88 ALOX5 (0.43) LMNAALOX5PTGESPPARGTDP1
Styrene SCHEMBL8635873 0.85 AKR1C3 (0.42) LMNAALOX5PTGESPPARGTDP1
Styrene SCHEMBL17065130 0.84 LMNA (0.47) LMNAALOX5PTGESPPARGTDP1
Styrene SCHEMBL5270544 0.84 LMNA (0.47) LMNAALOX5PTGESPPARGTDP1
Styrene SCHEMBL258132 0.84 LMNA (0.47) LMNAALOX5PTGESPPARGTDP1
Styrene SCHEMBL28040202 0.83 ALDH1A1 (0.50) LMNATDP1ALDH1A1TSHRCES2
Styrene SCHEMBL6982750 0.83 ALOX5 (0.40) LMNAALOX5PTGESPPARGTDP1
Styrene SCHEMBL4632285 0.82 TDP1 (0.50) LMNATDP1ALDH1A1CES2CES1
SCHEMBL1786246 0.80 ALOX5 (0.59) LMNAALOX5PTGESPPARGTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0171911-A1 Preparation of toner particles XEROX CORPORATION (US) 1986-02-19 EP claimed
US-5108863-A Processes for the preparation of encapsulated toner compositions XEROX CORPORATION (US) 1992-04-28 US disclosed
US-5035970-A Encapsulated toner compositions and processes thereof XEROX CORPORATION (US) 1991-07-30 US disclosed
US-4954412-A Processes for the preparation of encapsulated toner compositions XEROX CORPORATION (US) 1990-09-04 US disclosed