Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502356 | 0.88 | ATM (0.39) | ATMSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9373616 | 0.83 | MAPT (0.36) | ATMALDH1A1MAPTTDP1ALOX5 | |
| SCHEMBL3520478 | 0.80 | ATM (0.38) | ATMSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29012480 | 0.77 | MAPT (0.39) | ATMSMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL29012467 | 0.77 | MAPT (0.36) | ATMSMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL10549543 | 0.77 | GPR84 (0.35) | CTSVCTSLKCNH2GPR84SMN1; SMN2 | |
| SCHEMBL28058464 | 0.77 | NLRP3 (0.43) | ATMSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6686096 | 0.75 | ATM (0.37) | CTSVCTSLKCNH2PTPN1ATM | |
| SCHEMBL8627608 | 0.75 | PTPN1 (0.34) | CTSVCTSLKCNH2PTPN1GPR84 | |
| SCHEMBL10911386 | 0.73 | KAT2B (0.35) | ATMSMN1; SMN2ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085369-A | 3-aryloxoindole derivative and synthetic method thereof | UNIV EAST CHINA NORMAL | 2015-11-25 | — | — | CN | disclosed |
| CN-105085369-A | 3-aryloxoindole derivative and synthetic method thereof | UNIV EAST CHINA NORMAL | 2015-11-25 | — | — | CN | disclosed |