Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502356 | 0.81 | ATM (0.39) | NLRP3ATMMAPTKMT2AALDH1A1 | |
| SCHEMBL28149071 | 0.81 | NLRP3 (0.32) | NLRP3ATMMAPTKMT2AALDH1A1 | |
| SCHEMBL3520478 | 0.80 | ATM (0.38) | NLRP3ATMMAPTKMT2AALDH1A1 | |
| SCHEMBL29012480 | 0.77 | MAPT (0.39) | NLRP3ATMMAPTKMT2AALDH1A1 | |
| SCHEMBL29012467 | 0.77 | MAPT (0.36) | NLRP3ATMMAPTKMT2AALDH1A1 | |
| SCHEMBL22410854 | 0.77 | MAPT (0.36) | NLRP3ATMMAPTKMT2AALDH1A1 | |
| SCHEMBL28041004 | 0.77 | CTSV (0.37) | ATMMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9373616 | 0.73 | MAPT (0.36) | NLRP3ATMMAPTKMT2AALDH1A1 | |
| SCHEMBL10911386 | 0.73 | KAT2B (0.35) | ATMMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL6660995 | 0.73 | MAPT (0.37) | NLRP3ATMMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105439937-A | Method for synthesizing 3-halogenoindoles-2-one compound | UNIV SOOCHOW | 2016-03-30 | — | — | CN | disclosed |