Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041004 | 0.75 | CTSV (0.37) | PTPN1CTSVCTSLKCNH2ATM | |
| SCHEMBL6686096 | 0.73 | ATM (0.37) | PTPN1CTSVCTSLKCNH2ATM | |
| SCHEMBL10502356 | 0.66 | ATM (0.39) | ATMSMN1; SMN2LMNA | |
| SCHEMBL8601000 | 0.65 | ATM (0.33) | ATMLMNA | |
| SCHEMBL17022467 | 0.65 | MAPT (0.45) | PTPN1ATM | |
| SCHEMBL28134315 | 0.63 | ALDH1A1 (0.39) | ATMSMN1; SMN2LMNA | |
| SCHEMBL3520478 | 0.62 | ATM (0.38) | ATMSMN1; SMN2LMNA | |
| SCHEMBL8525118 | 0.62 | MAPT (0.35) | ATMLMNA | |
| SCHEMBL28890950 | 0.62 | ALDH1A1 (0.38) | ATMSMN1; SMN2LMNA | |
| SCHEMBL10718655 | 0.60 | MAPT (0.49) | ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853622-A1 | PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO 3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997044342-A1 | PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-11-27 | — | — | WO | disclosed |