Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122776 | 0.94 | ALDH1A1 (0.37) | — | |
| Silver SCHEMBL7021897 | 0.94 | — | — | |
| Silver SCHEMBL11460248 | 0.94 | — | — | |
| Potassium Ion SCHEMBL544827 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL9431945 | 0.77 | — | — | |
| Acetic Acid SCHEMBL28873642 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL8131901 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL8131905 | 0.73 | ALDH1A1 (0.44) | — | |
| Fumaric Acid SCHEMBL105898 | 0.71 | CA1 (0.50) | — | |
| Fumaric Acid SCHEMBL6468117 | 0.71 | CA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017256-A | Polyfluorinated compound Bruton tyrosine kinase inhibitor | ZHEJIANG DAOMING PHARMACEUTICAL CO LTD | 2015-11-04 | — | — | CN | disclosed |