SCHEMBL2804151

SCHEMBL2804151

Cc1c(C(=O)O)sc2sc(C(=O)O)c(C)c12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 8/20 0.45
BCAT2 O15382 2/20 0.44
PKM P14618 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HPGD P15428 3/20 0.43
LMNA P02545 1/20 0.43
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
USP2 O75604 1/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2808132 0.78 GPR35 (0.52) GPR35BCAT2PKMNPSR1RXFP1
SCHEMBL7526078 0.78 GPR35 (0.47) GPR35BCAT2PKMNPSR1RXFP1
Hydrochloric Acid SCHEMBL11597163 0.76 GPR35 (0.50) GPR35BCAT2PKMNPSR1RXFP1
SCHEMBL15342922 0.75 GPR35 (0.67) GPR35BCAT2PKMNPSR1RXFP1
SCHEMBL31207537 0.73 GPR35 (0.48) GPR35BCAT2PKMNPSR1RXFP1
SCHEMBL16311870 0.72 GPR35 (0.50) GPR35BCAT2PKMNPSR1RXFP1
SCHEMBL16827248 0.72 MAPT (0.56) PKMRXFP1HPGDLMNAALDH1A1
SCHEMBL17433849 0.71 PDE10A (0.51) GPR35PKMNPSR1RXFP1
SCHEMBL5122666 0.70 GPR35 (0.47) GPR35PKMNPSR1RXFP1LMNA
SCHEMBL14132708 0.70 GPR35 (0.59) GPR35BCAT2PKMNPSR1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119092810-A High-conductivity polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2024-12-06 CN claimed
CN-114903028-B Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2023-10-17 CN claimed
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN claimed
CN-113402727-B Terbium (III) loaded zinc-based metal organic framework and preparation and application thereof 云南师范大学 2022-07-12 CN claimed
CN-113402727-A Terbium (III) loaded zinc-based metal organic framework and preparation and application thereof 云南师范大学 2021-09-17 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-119092810-A High-conductivity polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2024-12-06 CN disclosed
CN-114903028-B Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2023-10-17 CN disclosed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN disclosed
US-20050090640-A1 Mono-, oligo-and polythieno[2,3-b]thiophenes FLEXENABLE TECHNOLOGY LIMITED (GB) 2005-04-28 US disclosed
EP-1510535-A1 Mono-, Oligo- and Polythieno(2,3-b)thiophenes MERCK PATENT GmbH (DE) 2005-03-02 EP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
EP-1083918-A1 NOVEL THERAPEUTIC AGENTS THAT MODULATE 5-HT RECEPTORS Advanced Medicine, Inc. (US) 2001-03-21 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
WO-1999064044-A1 NOVEL THERAPEUTIC AGENTS THAT MODULATE 5-HT RECEPTORS ADVANCED MEDICINE, INC. (US) 1999-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 GPR35 2001/4885BCAT2 1230/4885PKM 82/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA GPR35 1026/4885BCAT2 305/4885PKM 215/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA GPR35 2102/4885BCAT2 25/4885PKM 3571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.