SCHEMBL28041745

SCHEMBL28041745

CC(C)(OC(N)=O)[C@@H](CCO)c1ccccc1F

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
GAA P10253 1/20 0.37
CYP3A4 P08684 1/20 0.35
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
ALDH1A1 P00352 3/20 0.34
ADRB2 P07550 2/20 0.34
ADRB1 P08588 2/20 0.34
ADRB3 P13945 2/20 0.34
LMNA P02545 1/20 0.34
CNR2 P34972 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KCNN4 O15554 1/20 0.33
MC4R P32245 2/20 0.32
CNR1 P21554 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041742 0.87 ALDH1A1 (0.38) CES2CES1GAACYP3A4IDO1
SCHEMBL28041741 0.84 ADRB2 (0.40) ADRB2ADRB1KMT2A
SCHEMBL28041560 0.84
SCHEMBL28041531 0.84 ADRB2 (0.40) ADRB2ADRB1KMT2A
SCHEMBL28041547 0.83 ALDH1A1 (0.33) CES2CES1GAACYP3A4IDO1
SCHEMBL27664743 0.80 RIPK1 (0.42) GAACNR2CNR1PKM
SCHEMBL28041724 0.76
SCHEMBL27821809 0.75 DPP4 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL27535159 0.69 SRR (0.40) CYP3A4PKM
SCHEMBL10216947 0.69 CTSK (0.46) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209027-A Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes BIO PHARM SOLUTIONS CO LTD 2015-12-30 CN disclosed