Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | BAX | Q07812 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071379 | 0.85 | ALDH1A1 (0.50) | TSHR | |
| SCHEMBL9813951 | 0.80 | LTA4H (0.52) | LTA4HNR1H2BAXPPARGFFAR1 | |
| SCHEMBL17157130 | 0.79 | LTA4H (0.47) | LTA4HNR1H2BAXPPARGFFAR1 | |
| SCHEMBL11506283 | 0.77 | LTA4H (0.52) | LTA4HNR1H2BAXPPARGFFAR1 | |
| SCHEMBL13167017 | 0.76 | LTA4H (0.50) | LTA4HNR1H2BAXSRD5A2TSHR | |
| SCHEMBL8024062 | 0.74 | ALDH1A1 (0.72) | LTA4HNR1H2BAXPPARGFFAR1 | |
| SCHEMBL2088942 | 0.74 | LTA4H (0.58) | LTA4HNR1H2BAXPPARGFFAR1 | |
| SCHEMBL8994543 | 0.73 | TSHR (0.64) | LTA4HNR1H2BAXPPARGFFAR1 | |
| SCHEMBL9252738 | 0.72 | LTA4H (0.61) | LTA4HNR1H2BAXFFAR1SRD5A2 | |
| SCHEMBL891493 | 0.71 | FFAR1 (0.69) | LTA4HPPARGFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008344-A | Bruton's tyrosine kinase inhibitors | PFIZER | 2015-10-28 | — | — | CN | disclosed |