SCHEMBL280420

SCHEMBL280420

c1ccc2c(c1)c1ccccc1n2-c1ccc2oc3ccc(-c4ccc5oc6ccc(-n7c8ccccc8c8ccccc87)cc6c5c4)cc3c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
CASP3 P42574 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
PLA2G10 O15496 1/20 0.36
AHR P35869 1/20 0.36
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15780991 1.00 KDM4E (0.46) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL2628401 1.00 KDM4E (0.46) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL10041327 0.98 KDM4E (0.44) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL13383764 0.98 KDM4E (0.44) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL24813192 0.97 KDM4E (0.47) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL14733862 0.97 KDM4E (0.43) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL15780988 0.97 KDM4E (0.45) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL10038496 0.97 KDM4E (0.47) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL10348589 0.97 KDM4E (0.45) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1
SCHEMBL18266020 0.97 KDM4E (0.43) KDM4EATML3MBTL1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2023-12-05 US disclosed
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2023-12-05 US disclosed
US-11818950-B2 Organic electroluminescence element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-14 US disclosed
US-11818950-B2 Organic electroluminescence element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-14 US disclosed
US-20230026258-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS UDC IRELAND LTD (IE) 2023-01-26 US disclosed
EP-3126371-B1 METAL COMPLEXES, COMPRISING CARBENE LIGANDS HAVING AN O-SUBSTITUTED NON-CYCLOMETALATED ARYL GROUP AND THEIR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2021-11-10 EP disclosed
US-20210126207-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS UDC IRELAND LTD (IE) 2021-04-29 US disclosed
US-10916716-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2021-02-09 US disclosed
US-20200411770-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-12-31 US disclosed
US-10370396-B2 Metal complexes, comprising carbene ligands having an O-substituted non-cyclometallated aryl group and their use in organic light emitting diodes UDC IRELAND LIMITED (IE) 2019-08-06 US disclosed
US-20090091253-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-09 US disclosed
US-20090091253-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-09 US disclosed
US-20090017330-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed
US-20090017330-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed
EP-1998387-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-12-03 EP disclosed
EP-1998388-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-12-03 EP disclosed
US-20080238305-A1 WHITE LIGHT EMITTING ORGANIC ELECTROLUMINESCENT ELEMENT AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-10-02 US disclosed
US-20080238305-A1 WHITE LIGHT EMITTING ORGANIC ELECTROLUMINESCENT ELEMENT AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-10-02 US disclosed
EP-1970976-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-09-17 EP disclosed
EP-1947911-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200411770-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, ILF2, TCF7L2 KDM4E 2679/4885ATM 2654/4885L3MBTL1 413/4885
US-20230026258-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4573/4885ATM 3351/4885L3MBTL1 2835/4885
US-20090017330-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME ICMT, ORAI2, ILK KDM4E 3242/4885ATM 3240/4885L3MBTL1 580/4885
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4573/4885ATM 3351/4885L3MBTL1 2835/4885
US-10370396-B2 Metal complexes, comprising carbene ligands having an O-substituted non-cyclometallated aryl group and their use in organic light emitting diodes ICOSLG, CD40LG, OCIAD1 KDM4E 3913/4885ATM 3363/4885L3MBTL1 1361/4885
US-20210126207-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4573/4885ATM 3351/4885L3MBTL1 2835/4885
US-10916716-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4573/4885ATM 3351/4885L3MBTL1 2835/4885
US-11818950-B2 Organic electroluminescence element CCNE2, KCNN2, LEF1 KDM4E 2668/4885ATM 1956/4885L3MBTL1 437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.