Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.66 |
| ▸ | HTR1A | P08908 | 4/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | HTR6 | P50406 | 6/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28042822 | 0.90 | SLC6A4 (0.54) | SLC6A4HTR1ASLC6A2SLC6A3HTR6 | |
| SCHEMBL28211515 | 0.81 | SLC6A4 (0.46) | SLC6A4HTR1ASLC6A2SLC6A3HTR2C | |
| SCHEMBL4673484 | 0.80 | HTR1A (1.00) | SLC6A4HTR1ASLC6A2SLC6A3HTR6 | |
| SCHEMBL5043732 | 0.80 | ADRB2 (0.49) | SLC6A4HTR1ASLC6A2SLC6A3HTR6 | |
| SCHEMBL14015442 | 0.78 | HTR6 (0.57) | HTR6HTR2CADRB2NCF1HTR3A | |
| SCHEMBL31652205 | 0.78 | HTR6 (0.57) | HTR6HTR2CADRB2NCF1HTR3A | |
| SCHEMBL28042821 | 0.77 | RXRA (0.46) | SLC6A4HTR2CHTR2BRXRARXRB | |
| SCHEMBL30337054 | 0.76 | HTR1A (0.67) | SLC6A4HTR1ASLC6A2SLC6A3HTR6 | |
| SCHEMBL17305374 | 0.75 | TLR9 (0.49) | RXRARXRBRXRGMAPTTACR1 | |
| SCHEMBL17658996 | 0.74 | HTR1A (0.72) | SLC6A4HTR1ASLC6A2SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461635-B | Phenylpiperazine derivatives and its application method and purposes | 乳源瑶族自治县大众药品贸易有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-105461635-A | Phenylpiperazine derivatives, using method thereof and uses of the derivatives | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG MEDICINE TRADE CO LTD | 2016-04-06 | — | — | CN | disclosed |