Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.43 |
| ▸ | HTR3B | O95264 | 2/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042678 | 0.81 | HTR6 (0.44) | HTR6ALDH1A1HTR3AHTR3EHTR3B | |
| SCHEMBL31652205 | 0.80 | HTR6 (0.57) | HTR6ADRB2NCF1ALDH1A1HTR3A | |
| SCHEMBL14015442 | 0.80 | HTR6 (0.57) | HTR6ADRB2NCF1ALDH1A1HTR3A | |
| SCHEMBL27974537 | 0.79 | HTR3A (0.59) | HTR6HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5043732 | 0.78 | ADRB2 (0.49) | HTR6ADRB2NCF1ALDH1A1HTR3A | |
| SCHEMBL27605977 | 0.75 | HTR3E (0.44) | ALDH1A1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL13179908 | 0.74 | HTR3A (0.58) | HTR6ADRB2NCF1ALDH1A1HTR3A | |
| SCHEMBL27849400 | 0.73 | PTGDR2 (0.48) | HTR6SIGMAR1HTR2C | |
| SCHEMBL6034322 | 0.73 | GPR119 (0.48) | HTR6ADRB2NCF1ALDH1A1HTR3A | |
| SCHEMBL2857961 | 0.73 | ADRB2 (0.49) | HTR6ADRB2NCF1ALDH1A1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461635-A | Phenylpiperazine derivatives, using method thereof and uses of the derivatives | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG MEDICINE TRADE CO LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-105294554-A | Phenylpiperazine derivative, use method and uses thereof | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG DRUG TRADING CO LTD | 2016-02-03 | — | — | CN | disclosed |