Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824391 | 0.89 | LMNA (0.46) | MAPTTSHRMAPK1HSD17B10KDM4E | |
| SCHEMBL28043071 | 0.85 | ABL1 (0.52) | NPSR1MTORMAPTTSHRMAPK1 | |
| SCHEMBL16711121 | 0.79 | PDPK1 (0.58) | NPSR1MTORMAPTTSHRMAPK1 | |
| SCHEMBL16013236 | 0.79 | NPC1 (0.50) | NPSR1SYKMTORMAPTTSHR | |
| SCHEMBL16013548 | 0.79 | PIK3CA (0.48) | NPSR1SYKMTORMAPTTSHR | |
| SCHEMBL28042885 | 0.74 | GALR2 (0.51) | MAPTHSD17B10KDM4EMCHR1 | |
| SCHEMBL16711109 | 0.71 | HRH4 (0.52) | MTORMAPTTSHRHSD17B10KDM4E | |
| SCHEMBL4358342 | 0.70 | ABL1 (0.56) | MTORMAPTTDP1KDM4EPIK3CA | |
| SCHEMBL3451261 | 0.70 | MTOR (0.63) | MTORSMG1MAPTCNR2PIK3CA | |
| SCHEMBL2469738 | 0.69 | PIK3CA (0.56) | SYKPIK3CAPIK3CBPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |