Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946378 | 0.78 | CYP3A4 (0.61) | CYP3A4ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL4584939 | 0.78 | CYP3A4 (0.61) | CYP3A4ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL5049130 | 0.76 | CYP3A4 (0.59) | CYP3A4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28662 | 0.76 | CYP3A4 (1.00) | CYP3A4ALDH1A1HPGDKMT2AMEN1 | |
| Benzophenone SCHEMBL5566782 | 0.75 | ALDH1A1 (0.61) | CYP3A4ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL6695468 | 0.75 | CYP3A4 (0.62) | CYP3A4ALDH1A1HPGDHRH1LMNA | |
| SCHEMBL29507760 | 0.75 | CYP3A4 (0.62) | CYP3A4ALDH1A1HPGDHRH1LMNA | |
| Acetone SCHEMBL11800599 | 0.74 | CYP3A4 (0.76) | CYP3A4ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL24495889 | 0.74 | PLA2G4A (0.41) | CYP3A4ALDH1A1HPGDHRH1LMNA | |
| SCHEMBL29150349 | 0.74 | CYP3A4 (0.55) | CYP3A4ALDH1A1HPGDLMNAPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105126653-B | Three-dimensional fusion sediment polyamide forward osmosis membrane, preparation method and applications | 清华大学 | 2018-02-09 | — | — | CN | disclosed |
| CN-205042367-U | Positive osmotic membrane of three -dimensional fused deposition polyamide | UNIV TSINGHUA | 2016-02-24 | — | — | CN | disclosed |
| CN-105126653-A | Three-dimensional fused deposition polyamide forward-osmosis membrane as well as preparation method and application thereof | UNIV TSINGHUA | 2015-12-09 | — | — | CN | disclosed |