SCHEMBL2946378

SCHEMBL2946378

C=CCn1c(=O)n(Cc2ccccc2)c(=O)n(Cc2ccccc2)c1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.61
ADORA3 P0DMS8 3/20 0.56
ADORA2A P29274 1/20 0.56
ADORA1 P30542 1/20 0.56
GSK3A P49840 3/20 0.50
GSK3B P49841 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
PKM P14618 1/20 0.46
CCNB2 O95067 1/20 0.46
CDK1 P06493 1/20 0.46
CCNB1 P14635 1/20 0.46
CCNB3 Q8WWL7 1/20 0.46
P2RX4 Q99571 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
F2 P00734 1/20 0.45
PLG P00747 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4584939 1.00 CYP3A4 (0.61) CYP3A4ADORA3ADORA2AADORA1GSK3A
SCHEMBL11033311 0.90 CYP3A4 (0.70) CYP3A4ADORA3ADORA2AADORA1KDM4E
SCHEMBL1284803 0.85 CYP3A4 (0.61) CYP3A4ADORA3ADORA2AADORA1KDM4E
SCHEMBL8985073 0.83 GSK3B (0.67) CYP3A4GSK3AGSK3BKDM4EMAPT
SCHEMBL17154512 0.81 CYP3A4 (0.57) CYP3A4ADORA3ADORA2AADORA1GSK3A
SCHEMBL31122814 0.80 ADORA3 (0.46) CYP3A4ADORA3ADORA2AADORA1KDM4E
SCHEMBL5049130 0.79 CYP3A4 (0.59) CYP3A4GSK3AGSK3BKDM4EMAPT
SCHEMBL28662 0.78 CYP3A4 (1.00) CYP3A4ADORA3ADORA2AKDM4EMAPT
SCHEMBL29507760 0.78 CYP3A4 (0.62) CYP3A4KDM4EL3MBTL1SMN1; SMN2LMNA
SCHEMBL6695468 0.78 CYP3A4 (0.62) CYP3A4KDM4EL3MBTL1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3528046-B1 POSITIVE PHOTOSENSITIVE COMPOSITION AND THIN FILM TRANSISTOR KANEKA CORP (JP) 2020-09-09 EP disclosed
EP-3528046-A1 POSITIVE PHOTOSENSITIVE COMPOSITION AND THIN FILM TRANSISTOR Kaneka Corporation (JP) 2019-08-21 EP disclosed
EP-2871523-B1 POSITIVE PHOTOSENSITIVE COMPOSITION AND THIN FILM TRANSISTOR KANEKA CORP (JP) 2019-05-08 EP disclosed
US-9793456-B2 Molded resin body for surface-mounted light-emitting device, manufacturing method thereof, and surface-mounted light-emitting device KANEKA CORPORATION (JP) 2017-10-17 US disclosed
US-9588425-B2 Positive photosensitive composition, thin film transistor, and compound KANEKA CORPORATION (JP) 2017-03-07 US disclosed
US-20170023861-A1 POSITIVE PHOTOSENSITIVE COMPOSITION, THIN FILM TRANSISTOR, AND COMPOUND KANEKA CORP (JP) 2017-01-26 US disclosed
US-9494861-B2 Positive photosensitive composition, thin film transistor, and compound KANEKA CORPORATION (JP) 2016-11-15 US disclosed
US-9496468-B2 Curable resin composition, curable resin composition tablet, molded body, semiconductor package, semiconductor component and light emitting diode KANEKA CORPORATION (JP) 2016-11-15 US disclosed
EP-1803761-B1 Ring-opened copolymer, hydrogenated ring-opened copolymer, process for producing thereof, and compositions ZEON CORP (JP) 2016-04-27 EP disclosed
US-9178120-B2 Curable resin composition, curable resin composition tablet, molded body, semiconductor package, semiconductor component and light emitting diode KANEKA CORPORATION (JP) 2015-11-03 US disclosed
EP-1609835-A1 CURING COMPOSITION AND METHOD FOR PREPARING SAME, LIGHT-SHIELDING PASTE, LIGHT-SHIELDING RESIN AND METHOD FOR PRODUCING SAME, PACKAGE FOR LIGHT-EMITTING DIODE, AND SEMICONDUCTOR DEVICE KANEKA CORPORATION (JP) 2005-12-28 EP disclosed
US-6955848-B2 Curable composition and multilayered circuit substrate ZEON CORPORATION (JP) 2005-10-18 US disclosed
US-20050209400-A1 1,3,5,7-tetramethylcyclotetrasiloxane and triallyl isocyanurate, a hydrosilylation catalyst, a silane coupling agent and/or an epoxy group-containing compound, and a silanol condensation catalyst KANEKA CORPORATION (JP) 2005-09-22 US disclosed
EP-1505121-A1 HARDENABLE COMPOSITION, HARDENING PRODUCT, PROCESS FOR PRODUCING THE SAME AND LIGHT EMITTING DIODE SEALED WITH THE HARDENING PRODUCT KANEKA CORPORATION (JP) 2005-02-09 EP disclosed
US-20040152843-A1 Open-ring copolymer, hydrogenated open-ring copolymer, process for production of both, and compositions ZEON CORPORATION (JP) 2004-08-05 US disclosed
EP-1408064-A1 OPEN-RING COPOLYMER, HYDROGENATED OPEN-RING COPOLYMER, PROCESSES FOR PRODUCTION OF BOTH, AND COMPOSITIONS Zeon Corporation (JP) 2004-04-14 EP disclosed
US-20040029043-A1 Process for producing circuit substrates ZEON CORPORATION (JP) 2004-02-12 US disclosed
US-20040025743-A1 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2004-02-12 US disclosed
US-20030146421-A1 Curable composition and multilayered circuit substrate ZEON CORPORATION (JP) 2003-08-07 US disclosed
EP-1275695-A1 CURABLE COMPOSITION AND MULTILAYERED CIRCUIT SUBSTRATE Zeon Corporation (JP) 2003-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170023861-A1 POSITIVE PHOTOSENSITIVE COMPOSITION, THIN FILM TRANSISTOR, AND COMPOUND ASIC3, ASIC1, HCN4 CYP3A4 2917/4885ADORA3 2964/4885ADORA2A 4023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.