Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367263 | 0.77 | KMT2A (0.47) | PKMLMNAPOLBMAPK1MTNR1A | |
| SCHEMBL11269432 | 0.73 | PKM (0.46) | PKMLMNAPOLBMAPK1MTNR1A | |
| SCHEMBL6965136 | 0.71 | LMNA (0.46) | PKMLMNAPOLBMAPK1ALDH1A1 | |
| SCHEMBL27684874 | 0.70 | LMNA (0.49) | PKMLMNAMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8432279 | 0.69 | SMN1; SMN2 (0.43) | PKMLMNAPOLBMAPK1ALDH1A1 | |
| SCHEMBL8793840 | 0.68 | FFAR1 (0.47) | PKMLMNAALDH1A1L3MBTL1GAA | |
| SCHEMBL8555710 | 0.68 | LMNA (0.44) | PKMLMNAPOLBMAPK1MTNR1A | |
| SCHEMBL8329718 | 0.68 | PIN1 (0.50) | PKMPOLBALDH1A1MAPTKDM4E | |
| SCHEMBL6686346 | 0.67 | EPHX1 (0.45) | PKMLMNAPOLBMAPK1L3MBTL1 | |
| Acetic Acid SCHEMBL22497414 | 0.67 | LMNA (0.47) | PKMLMNAPOLBMAPK1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189463-A | Pyridazinone compound and process for producing the same | TAKEDA PHARMACEUTICAL | 2015-12-23 | — | — | CN | disclosed |