Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043834 | 0.73 | PKM (0.43) | PKMLMNAMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL3654892 | 0.72 | HSD11B1 (0.50) | MTNR1AMTNR1BL3MBTL1ALDH1A1POLB | |
| SCHEMBL3035291 | 0.72 | PIN1 (0.50) | PKMALDH1A1MAPTKDM4ESMN1; SMN2 | |
| Acetic Acid SCHEMBL22497414 | 0.71 | LMNA (0.47) | PKMLMNAMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL820641 | 0.71 | CYP2C19 (0.45) | PKMLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7619692 | 0.71 | LMNA (0.54) | LMNAMTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL2443856 | 0.71 | MTNR1A (0.46) | MTNR1AMTNR1BPOLB | |
| SCHEMBL11302862 | 0.70 | SMN1; SMN2 (0.41) | PKMLMNAMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL11495800 | 0.69 | CYP2C9 (0.44) | PKMLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL27684874 | 0.69 | LMNA (0.49) | PKMLMNAMTNR1AMTNR1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342705-A | CONTAINING CARBONYL OR CYANO FUNCTIONAL GROUPS, USEFUL AS VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |