SCHEMBL28044205

SCHEMBL28044205

O=[N+]([O-])c1cccc(Cl)c1C(Br)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.44
CYP1A2 P05177 1/20 0.42
ALDH1A1 P00352 7/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
PKM P14618 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 4/20 0.39
PTPRC P08575 1/20 0.38
S100A4 P26447 1/20 0.38
GPR35 Q9HC97 1/20 0.38
TSHR P16473 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
VCAM1 P19320 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27783994 0.76 HPGD (0.47) HPGDALDH1A1MAPTMEN1KMT2A
SCHEMBL9524433 0.75 VCAM1 (0.50) CYP1A2ALDH1A1MAPTMEN1KMT2A
SCHEMBL12985610 0.75 ALDH1A1 (0.49) HPGDCYP1A2ALDH1A1MAPTMEN1
SCHEMBL4690726 0.75 CYP1A2 (0.60) CYP1A2ALDH1A1MEN1KMT2AMAPK1
SCHEMBL27869963 0.75 HPGD (0.46) HPGDCYP1A2ALDH1A1MAPTMEN1
SCHEMBL7680328 0.74 ALDH1A1 (0.46) HPGDCYP1A2ALDH1A1MAPTMEN1
SCHEMBL7680313 0.74 ALDH1A1 (0.46) HPGDCYP1A2ALDH1A1MAPTMEN1
Benzene SCHEMBL28064387 0.73 HPGD (0.60) HPGDALDH1A1MAPTMEN1KMT2A
SCHEMBL16268196 0.71 GPR35 (0.48) CYP1A2ALDH1A1MAPTL3MBTL1TDP1
SCHEMBL29962795 0.71 HPGD (0.62) HPGDALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105111148-A 2-[(N-para-chlorophenyl)-3-pyrazole oxymethyl]nitrobenzene and preparation method therefor and application thereof ANHUI COSTAR BIO CHEMICAL CO LTD 2015-12-02 CN claimed
CN-105111148-A 2-[(N-para-chlorophenyl)-3-pyrazole oxymethyl]nitrobenzene and preparation method therefor and application thereof ANHUI COSTAR BIO CHEMICAL CO LTD 2015-12-02 CN disclosed