SCHEMBL2804428

SCHEMBL2804428

O=C(O)CCNC(=O)Cc1ccccc1CCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.53
TAAR1 Q96RJ0 1/20 0.48
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 2/20 0.46
LMNA P02545 1/20 0.45
KEAP1 Q14145 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MME P08473 1/20 0.43
ACE P12821 1/20 0.43
PTGER1 P34995 1/20 0.43
PTGER4 P35408 1/20 0.43
PTGER3 P43115 1/20 0.43
PTGER2 P43116 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415449 1.00 ATM (0.53) ATMTAAR1GAAHPGDTSHR
SCHEMBL2807016 0.87 ATM (0.45) ATMTAAR1KEAP1PTGER1PTGER4
SCHEMBL13602497 0.85 ATM (0.51) ATMTAAR1GAAHPGDTSHR
SCHEMBL3200958 0.85 AKR1B1 (0.58) ATMTAAR1GAAHPGDTSHR
SCHEMBL13689911 0.83 ATM (0.49) ATMTAAR1GAAHPGDTSHR
SCHEMBL8277252 0.83 ATM (0.49) ATMTAAR1GAAHPGDTSHR
SCHEMBL8019696 0.80 AKR1B1 (0.59) KEAP1PTGER1PTGER4PTGER3PTGER2
SCHEMBL59198 0.80 KEAP1 (0.65) KEAP1PTGER1PTGER4PTGER3PTGER2
SCHEMBL3207835 0.79 ATM (0.80) ATMGAAHPGDTSHRLMNA
SCHEMBL3205671 0.78 TAAR1 (0.72) TAAR1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2018119500-A1 VISCOELASTIC COSMETIC COMPOSITIONS L'OREAL (FR) 2018-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 ATM 1985/4885TAAR1 3852/4885GAA 342/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA ATM 3868/4885TAAR1 2005/4885GAA 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.