Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467830 | 0.88 | MAPT (0.44) | ALDH1A1MAPTHPGDKDM4ERAB9A | |
| SCHEMBL28044566 | 0.81 | SIRT6 (0.41) | MYCALDH1A1MAPTGAAHPGD | |
| SCHEMBL3809507 | 0.78 | ALDH1A1 (0.53) | MYCALDH1A1MAPTGAAHPGD | |
| SCHEMBL7052909 | 0.77 | RAB9A (0.43) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL27808166 | 0.77 | NPC1 (0.52) | MYCALDH1A1MAPTGAAHPGD | |
| SCHEMBL7051580 | 0.74 | HPGD (0.50) | ALDH1A1MAPTHPGDNPC1RAB9A | |
| SCHEMBL7468705 | 0.74 | KDM4E (0.41) | ALDH1A1MAPTGAAKDM4ERAB9A | |
| SCHEMBL1098022 | 0.74 | MYC (0.46) | MYCALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL17158206 | 0.72 | ALDH1A1 (0.50) | MYCALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL17158204 | 0.72 | ALDH1A1 (0.50) | MYCALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594862-B | Substituted indazole derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |