Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052909 | 0.87 | RAB9A (0.43) | KDM4EMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL7467830 | 0.85 | MAPT (0.44) | KDM4EMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL7463261 | 0.84 | CASP3 (0.42) | KDM4EMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL7468709 | 0.80 | PRKD3 (0.45) | KDM4EMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL7466384 | 0.80 | OPRK1 (0.40) | KDM4EMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL7051580 | 0.78 | HPGD (0.50) | MAPTALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL382515 | 0.74 | HTT (0.51) | KDM4EMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL5864094 | 0.74 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL15214404 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL5652256 | 0.70 | KDM4E (0.51) | KDM4EMAPTALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |