Styrene

Styrene

SCHEMBL28044575

C=COC(=O)CC.C=Cc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
ELANE P08246 1/20 0.39
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
CYP3A4 P08684 1/20 0.36
NR1I2 O75469 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
ADORA3 P0DMS8 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9664548 1.00 ALDH1A1 (0.48) ALDH1A1TSHRMEN1KMT2AELANE
Styrene SCHEMBL7747013 0.94 ALDH1A1 (0.42) ALDH1A1TSHRMEN1KMT2AELANE
SCHEMBL28273781 0.91 ALDH1A1 (0.42) ALDH1A1TSHRKMT2AKDM4ESMN1; SMN2
Styrene SCHEMBL28091036 0.86 ELANE (0.37) ALDH1A1TSHRMEN1KMT2AELANE
SCHEMBL28249301 0.85 TAS1R3 (0.38) ALDH1A1KMT2AKDM4ESMN1; SMN2TAS1R3
Styrene SCHEMBL28022925 0.84 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2AELANE
SCHEMBL28273783 0.84 CYP3A4 (0.37) ALDH1A1TSHRMEN1KMT2AELANE
Styrene SCHEMBL23392490 0.83 PKM (0.52) ALDH1A1TSHRMEN1KMT2AELANE
Styrene SCHEMBL28174472 0.83 ALDH1A1 (0.45) ALDH1A1TSHRMEN1KMT2AKDM4E
SCHEMBL9714809 0.83 LMNA (0.48) ALDH1A1MEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085764-B Polystyrene vinyl propionate and preparation method and application thereof 中国石油天然气股份有限公司 2017-12-05 CN disclosed
CN-105085764-B Polystyrene vinyl propionate and preparation method and application thereof 中国石油天然气股份有限公司 2017-12-05 CN disclosed
CN-105085764-A Polystyrene vinyl propionate and preparation method and application thereof PETROCHINA CO LTD 2015-11-25 CN disclosed