Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | AGXT | P21549 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565329 | 0.83 | AGXT (0.48) | IDO1AGXTTAAR1SMN1; SMN2 | |
| SCHEMBL4409731 | 0.83 | IDO1 (0.33) | IDO1AGXTTSHRALDH1A1MAPK1 | |
| SCHEMBL1315036 | 0.80 | IDO1 (0.46) | IDO1AGXTTSHRALDH1A1SLC6A2 | |
| SCHEMBL4410124 | 0.80 | IDO1 (0.31) | IDO1AGXT | |
| SCHEMBL31084123 | 0.78 | IDO1 (0.33) | IDO1 | |
| SCHEMBL31389095 | 0.76 | MMP3 (0.40) | IDO1TDP1 | |
| SCHEMBL7747937 | 0.75 | FDPS (0.33) | IDO1ALDH1A1TDP1 | |
| SCHEMBL6111479 | 0.74 | TSHR (0.48) | IDO1AGXTTSHRALDH1A1SLC6A2 | |
| SCHEMBL9709126 | 0.73 | ALDH1A1 (0.38) | IDO1AGXTALDH1A1 | |
| SCHEMBL19253313 | 0.72 | TSHR (0.44) | IDO1AGXTTSHRALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859745-A | Selective synthetic method of natural products Xylapyrroside A | 复旦大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105622496-A | Tetracycline compounds | TETRAPHASE PHARMACEUTICALS INC | 2016-06-01 | — | — | CN | disclosed |
| CN-102596898-B | tetracycline compound | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2016-01-27 | — | — | CN | disclosed |