Trinitrotoluene

Trinitrotoluene

SCHEMBL28045308

Cc1c([N+](=O)[O-])cc([N+](=O)[O-])cc1[N+](=O)[O-].Oc1ccccc1

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
GPR35 Q9HC97 6/20 0.54
TDP1 Q9NUW8 4/20 0.50
TSHR P16473 3/20 0.50
ALOX15 P16050 3/20 0.50
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
MAPK1 P28482 3/20 0.49
HPGD P15428 3/20 0.49
MAPT P10636 3/20 0.49
HSD17B10 Q99714 3/20 0.49
TP53 P04637 2/20 0.49
KDM4E B2RXH2 2/20 0.49
ALOX12 P18054 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TTR P02766 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
RECQL P46063 1/20 0.49
PMP22 Q01453 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trinitrotoluene SCHEMBL11327539 0.91 GPR35 (0.59) ALDH1A1GPR35TDP1TSHRALOX15
Trinitrotoluene SCHEMBL28223014 0.87 ALDH1A1 (0.61) ALDH1A1GPR35TDP1TSHRMEN1
Trinitrophenol SCHEMBL27538937 0.86 CRHBP (0.62) ALDH1A1GPR35TDP1TSHRALOX15
Dinitro Cresol SCHEMBL892354 0.85 ALDH1A1 (0.78) ALDH1A1GPR35TDP1TSHRALOX15
Trinitrotoluene SCHEMBL27786014 0.83 GPR35 (0.62) ALDH1A1GPR35TDP1TSHRALOX15
Phenol SCHEMBL27815806 0.83 TSHR (0.63) ALDH1A1TDP1TSHRALOX15MEN1
Trinitrotoluene SCHEMBL891182 0.83 ALDH1A1 (0.61) ALDH1A1GPR35TDP1TSHRALOX15
Trinitrotoluene SCHEMBL20676 0.83 ALDH1A1 (0.61) ALDH1A1GPR35TDP1TSHRALOX15
Phenol SCHEMBL28300096 0.82 TSHR (0.61) ALDH1A1GPR35TSHRALOX15MEN1
Trinitrotoluene SCHEMBL20984912 0.82 GPR35 (0.56) ALDH1A1GPR35TDP1TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105110447-A Application of Au/g-C3N4 nanocomposite UNIV NANJING SCIENCE & TECH 2015-12-02 CN disclosed