Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.34 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.34 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27880512 | 0.76 | ALDH1A1 (0.36) | NPC1RAB9ANFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL28553655 | 0.75 | GAA (0.33) | DRD2NPC1RAB9ANPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8158883 | 0.75 | TLR8 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8169170 | 0.75 | PSMB5 (0.32) | PSMB5 | |
| Hydrochloric Acid SCHEMBL6898339 | 0.72 | CYP1A2 (0.41) | CYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL813276 | 0.71 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL5684938 | 0.71 | EDNRB (0.38) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL4078640 | 0.69 | CYP11B1 (0.31) | — | |
| Bromide SCHEMBL27932887 | 0.68 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19DRD2 | |
| Iodide SCHEMBL27948578 | 0.68 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102597096-B | Melt blown fiber of polypropylene composition | BOREALIS AG (AT) | 2015-11-25 | — | — | CN | disclosed |