SCHEMBL914002

SCHEMBL914002

O=C1C(O)Oc2ccccc2N1O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AADAT Q8N5Z0 6/20 0.42
GOT1 P17174 1/20 0.42
KYAT1 Q16773 1/20 0.42
KYAT3 Q6YP21 1/20 0.42
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SIRT1 Q96EB6 1/20 0.36
P2RX4 Q99571 2/20 0.35
TSHR P16473 2/20 0.35
HTT P42858 1/20 0.35
ADK P55263 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29999046 1.00 AADAT (0.42) AADATGOT1KYAT1KYAT3KMT2A
SCHEMBL28045866 0.79 EGFR (0.41) KMT2AALDH1A1L3MBTL1P2RX4TSHR
2-Methyl-D-Diboa SCHEMBL13135829 0.79 ALDH1A1 (0.54) AADATKMT2AALDH1A1L3MBTL1NPC1
SCHEMBL30105900 0.79 RECQL (0.36) AADAT
SCHEMBL13812449 0.78 AADAT (0.47) AADATALDH1A1TSHR
SCHEMBL912624 0.74 KYAT1 (0.47) AADATKYAT1KYAT3KMT2AALDH1A1
SCHEMBL22631177 0.69 AADAT (0.58) AADATGOT1KYAT1KYAT3KMT2A
SCHEMBL27841958 0.66 KMT2A (0.34) KMT2AALDH1A1L3MBTL1SIRT1P2RX4
SCHEMBL29987450 0.65 MAOA (0.40) KMT2AALDH1A1P2RX4
SCHEMBL69727 0.65 RET (0.53) KMT2AALDH1A1NPC1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118782152-B Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2025-05-20 CN claimed
CN-118782152-A Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2024-10-15 CN claimed
EP-3447134-B1 INCREASED FUNGAL RESISTANCE IN CROP PLANTS KWS SAAT SE & CO KGAA (DE) 2023-10-11 EP claimed
WO-2023180613-A1 METHOD FOR PURIFYING BIOTECHNOLOGICALLY PRODUCED D-DIBOA UNIVERSIDAD DE CÁDIZ (ES) 2023-09-28 WO claimed
WO-2023082029-A1 METHOD FOR PREPARING AN EXTRACT BASED ON ACANTHUS LEAVES (ACANTHUS MOLLIS) AS A NATURAL FUNGICIDE AND INSECTICIDE BUZZETTI MORALES KARINA ANDREA (CL) 2023-05-19 WO claimed
US-20210204574-A1 Consumable Product Comprising Malted Wheat Lantmannen Functional Foods AB (SE) 2021-07-08 US claimed
CN-112770644-A Consumable product comprising malted wheat 兰特门内保健食品公司 2021-05-07 CN claimed
CN-118782152-B Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2025-05-20 CN disclosed
CN-117105918-B 1, 4-Benzoxazinone derivative with biological activity and preparation method and application thereof 河南师范大学 2025-03-18 CN disclosed
WO-2025030164-A1 METHOD FOR PROMOTING PLANT GROWTH AND MODULATING PLANT ARCHITECTURE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-06 WO disclosed
CN-118782152-A Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2024-10-15 CN disclosed
CN-111247243-B Increased fungal resistance in crop plants 科沃施种子欧洲股份两合公司 2024-08-06 CN disclosed
CN-117688479-A Composite fault diagnosis method based on improved distributed butterfly optimization algorithm 国网湖南省电力有限公司 2024-03-12 CN disclosed
US-20050255159-A1 Porous calcium phosphate networks for synthetic bone material UNIVERSITY OF MASSACHUSETTS 2005-11-17 US disclosed
US-20050250772-A1 Methods for inducing anti-anxiety and calming effects in animals and humans SAVANNA HEALTH LLC 2005-11-10 US disclosed
WO-2005102281-A2 POROUS CALCIUM PHOSPHATE NETWORKS FOR SYNTHETIC BONE MATERIAL UNIVERSITY OF MASSACHUSETTS (US) 2005-11-03 WO disclosed
US-20040209877-A1 Methods for augmenting immune defenses contemplating the administration of phenolic and indoleamine-like compounds for use in animals ans humans SEROCTIN RESEARCH & TECHNOLOGY, INC. 2004-10-21 US disclosed
US-20040192669-A1 Novel compounds for use in weight loss and appetite suppression in humans SEROCTIN RESEARCH & TECHNOLOGY, INC. 2004-09-30 US disclosed
US-3882107-A Zinc chelate of 2,4-dihydroxy-1,4(2H)-benzoxazine-3-one UNIV IOWA STATE RES FOUND INC 1975-05-06 US disclosed
US-3882107-A Zinc chelate of 2,4-dihydroxy-1,4(2H)-benzoxazine-3-one UNIV IOWA STATE RES FOUND INC 1975-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192669-A1 Novel compounds for use in weight loss and appetite suppression in humans CPT1B, FABP4, EGLN1 AADAT 205/4885GOT1 647/4885KYAT1 820/4885
US-20040209877-A1 Methods for augmenting immune defenses contemplating the administration of phenolic and indoleamine-like compounds for use in animals ans humans HAAO, HMOX1, IDO1 AADAT 26/4885GOT1 1247/4885KYAT1 1150/4885
US-20050250772-A1 Methods for inducing anti-anxiety and calming effects in animals and humans CALM1, HAAO, MYB AADAT 214/4885GOT1 1573/4885KYAT1 1720/4885
US-20210204574-A1 Consumable Product Comprising Malted Wheat FABP6, MLN, FABP2 AADAT 1317/4885GOT1 1170/4885KYAT1 2177/4885
US-20050255159-A1 Porous calcium phosphate networks for synthetic bone material BMP2, SOST, BMP6 AADAT 4798/4885GOT1 4325/4885KYAT1 4804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.