Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BCR | P11274 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16363280 | 0.82 | ALDH1A1 (0.78) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL2805235 | 0.82 | PRMT5 (0.49) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL2785338 | 0.80 | SRC (0.56) | GAASRCABL1BCRCYP1A2 | |
| SCHEMBL13087256 | 0.79 | GAA (0.78) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL31194480 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL31194520 | 0.76 | LMNA (0.59) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL2786472 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL31194508 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL13087419 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL2810178 | 0.74 | GAA (0.56) | MAPTGAASRCABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |