Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 8/20 | 0.48 |
| ▸ | HCK | P08631 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 4/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804593 | 0.82 | ALDH1A1 (0.54) | PRMT5ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL31194520 | 0.77 | LMNA (0.59) | ALDH1A1LMNAHTTSRCABL1 | |
| SCHEMBL31194480 | 0.76 | ALDH1A1 (0.54) | PRMT5ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL31194508 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL2786472 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL2785338 | 0.71 | SRC (0.56) | SRCHCKPIM1ABL1BCR | |
| SCHEMBL2810178 | 0.71 | GAA (0.56) | MAPTSRCBCDIN3DABL1BCR | |
| SCHEMBL21481606 | 0.70 | ADORA2A (0.52) | PRMT5ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL31385338 | 0.70 | ADORA2A (0.52) | PRMT5ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL2155009 | 0.68 | ABCG2 (0.53) | ABCG2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |