Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 7/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402148 | 0.89 | PNMT (0.49) | MAPTTLR9MEN1LMNARAB9A | |
| Ammonia Solution, Strong SCHEMBL27905491 | 0.81 | LMNA (0.62) | MAPTTLR9MEN1LMNARAB9A | |
| Phosphonic Acid SCHEMBL28853711 | 0.79 | TLR9 (0.56) | MAPTTLR9MEN1LMNARAB9A | |
| SCHEMBL1785799 | 0.78 | TDP2 (0.56) | MAPTTLR9MEN1LMNARAB9A | |
| SCHEMBL2616914 | 0.74 | TDP2 (0.73) | MAPTTLR9MEN1LMNARAB9A | |
| SCHEMBL987760 | 0.74 | TLR9 (0.79) | MAPTTLR9MEN1LMNARAB9A | |
| SCHEMBL30049268 | 0.74 | TLR9 (0.79) | MAPTTLR9MEN1LMNARAB9A | |
| SCHEMBL30709850 | 0.71 | PNMT (0.65) | MAPTTLR9MEN1LMNARAB9A | |
| SCHEMBL9483063 | 0.71 | PNMT (0.65) | MAPTTLR9MEN1LMNARAB9A | |
| SCHEMBL5544385 | 0.71 | TDP2 (0.49) | MAPTTLR9MEN1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315204-B | (2H) ketone derivatives of 7 amino, 1,4 dihydro-isoquinoline 3 and its preparation method and use | 中南大学 | 2018-02-09 | — | — | CN | disclosed |
| CN-105315204-A | 7-amino-1,4-dihydroisoquinoline-3(2H)-one derivative, synthetic method and application thereof | UNIV CENTRAL SOUTH | 2016-02-10 | — | — | CN | disclosed |