Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 7/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785799 | 0.77 | TDP2 (0.56) | TDP2MEN1KMT2ALMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL27905491 | 0.76 | LMNA (0.62) | TDP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL2616914 | 0.72 | TDP2 (0.73) | TDP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL1870205 | 0.72 | PNMT (0.54) | TDP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL30049268 | 0.72 | TLR9 (0.79) | TDP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL987760 | 0.72 | TLR9 (0.79) | TDP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL5548723 | 0.72 | MAPT (0.40) | TDP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL28046038 | 0.71 | MAPT (0.49) | TDP2MEN1KMT2ALMNAMAPT | |
| Phosphonic Acid SCHEMBL28853711 | 0.70 | TLR9 (0.56) | TDP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL30709850 | 0.70 | PNMT (0.65) | TDP2MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | disclosed |