Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956205 | 0.75 | CFD (0.33) | — | |
| SCHEMBL1013267 | 0.75 | ITGA4 (0.32) | — | |
| SCHEMBL19912814 | 0.74 | KDM4C (0.37) | HIF1A | |
| SCHEMBL31595785 | 0.73 | HIF1A (0.33) | HIF1A | |
| SCHEMBL1012752 | 0.69 | KMT2A (0.39) | — | |
| SCHEMBL13057196 | 0.67 | CYP11B2 (0.31) | — | |
| SCHEMBL26803600 | 0.67 | ACHE (0.33) | HIF1A | |
| SCHEMBL24178942 | 0.66 | ACHE (0.31) | — | |
| SCHEMBL21893804 | 0.66 | PI4KA (0.33) | — | |
| SCHEMBL21292266 | 0.66 | HTT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218448-B | A kind of synthetic method of the pyrazole carboxylic acid of 1 methyl, 3 difluoromethyl 4 | 江苏恒润制药有限公司 | 2017-11-07 | — | — | CN | disclosed |
| CN-105218448-A | A kind of synthetic method of 1-methyl-3-difluoromethyl-4-pyrazole carboxylic acid | Jiangsu hengrun pharmaceutical co ltd | 2016-01-06 | — | — | CN | disclosed |