Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 9/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943794 | 0.82 | HDAC3 (0.45) | LMNAHTT | |
| SCHEMBL28338447 | 0.80 | FFAR2 (0.47) | TSHRNFKB1ALOX15APEX1LMNA | |
| SCHEMBL27906641 | 0.79 | CYP2D6 (0.58) | SRCHIF1ATSHRNFKB1ALOX15 | |
| SCHEMBL3649813 | 0.77 | ESR1 (0.55) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL31359586 | 0.75 | ALDH1A1 (0.44) | SRCTSHRTDP1LMNAMAPT | |
| SCHEMBL27754462 | 0.74 | LMNA (0.49) | HIF1AKDM4ELMNACYP2D6 | |
| SCHEMBL9701361 | 0.73 | CYP2D6 (0.64) | SRCESR1ESR2PDCD1CD274 | |
| SCHEMBL28561150 | 0.73 | SRC (0.48) | SRCESR1ESR2PDCD1CD274 | |
| SCHEMBL27418947 | 0.72 | LTA4H (0.47) | TAAR1CYP3A4 | |
| SCHEMBL21048268 | 0.72 | ESR1 (0.50) | ESR1ESR2PDCD1CD274HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263987-A | Processes for enhancing flame retardance and chemical resistance of polymers | SABIC GLOBAL TECHNOLOGIES BV | 2016-01-20 | — | — | CN | disclosed |