Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805774 | 1.00 | F7 (0.44) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL28053583 | 0.80 | PLOD2 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL14138865 | 0.76 | F7 (0.38) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27479115 | 0.74 | NAPRT (0.47) | ALDH1A1MAPT | |
| SCHEMBL9260392 | 0.71 | L3MBTL1 (0.53) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL5199056 | 0.71 | TBXAS1 (0.51) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL415017 | 0.70 | — | — | |
| SCHEMBL31404951 | 0.70 | — | — | |
| SCHEMBL8296718 | 0.70 | — | — | |
| SCHEMBL27606596 | 0.70 | MAOA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105339355-A | Novel CYP17 inhibitor/antiandrogen | ORION CORP | 2016-02-17 | — | — | CN | disclosed |