Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.35 |
| ▸ | FGR | P09769 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825592 | 0.90 | PLA2G7 (0.38) | MEN1KMT2AALOX5GGT1ADORA2A | |
| SCHEMBL6932597 | 0.76 | ADORA2A (0.50) | MEN1KMT2AADORA2ACSNK1A1CSNK1D | |
| SCHEMBL3175328 | 0.71 | NOX1 (0.38) | MEN1KMT2AALOX5MAOATDP1 | |
| SCHEMBL8308624 | 0.70 | MEN1 (0.47) | MEN1KMT2AALOX5MAOATDP1 | |
| SCHEMBL28203049 | 0.70 | CYP3A4 (0.54) | ADORA2ACSNK1A1CSNK1DCSNK1G1FGR | |
| SCHEMBL9678804 | 0.70 | CYP3A4 (0.54) | ADORA2ACSNK1A1CSNK1DCSNK1G1FGR | |
| SCHEMBL28048870 | 0.70 | ALDH1A1 (0.39) | MEN1KMT2AALOX5TDP1CYP3A4 | |
| SCHEMBL9804804 | 0.69 | ALOX5 (0.38) | MEN1KMT2AALOX5MAOATDP1 | |
| SCHEMBL26665278 | 0.68 | ADORA2A (0.42) | MEN1KMT2AADORA2ACSNK1A1CSNK1D | |
| SCHEMBL2833308 | 0.68 | ALDH1A1 (0.45) | MEN1KMT2AADORA2ACSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189475-A | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LTD | 2015-12-23 | — | — | CN | claimed |
| CN-105189475-B | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | 动力欧勒德斯有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105189475-A | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LTD | 2015-12-23 | — | — | CN | disclosed |