SCHEMBL28048752

SCHEMBL28048752

Nc1ccc(OC(=O)c2ccc3[nH]c4ccc(C(=O)Oc5ccc(N)cc5)cc4c3c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.50
PRSS1 P07477 3/20 0.50
PRSS2 P07478 3/20 0.50
PRSS3 P35030 3/20 0.50
KMT2A Q03164 3/20 0.50
PKM P14618 1/20 0.50
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 2/20 0.47
HCRTR1 O43613 2/20 0.47
RAB9A P51151 2/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NR1H4 Q96RI1 1/20 0.46
GABRA1 P14867 1/20 0.45
GABRG2 P18507 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA3 P34903 1/20 0.45
GABRA2 P47869 1/20 0.45
KIF11 P52732 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9788371 0.80 F2 (0.58) F2PRSS1PRSS2PRSS3KMT2A
SCHEMBL28048707 0.80 KMT2A (0.59) KMT2APKMALDH1A1RAB9AMAPT
SCHEMBL347429 0.79 PRSS1 (0.71) F2PRSS1PRSS2PRSS3KMT2A
SCHEMBL346698 0.79 PRSS1 (0.71) F2PRSS1PRSS2PRSS3KMT2A
SCHEMBL107649 0.79 PRSS1 (0.71) F2PRSS1PRSS2PRSS3KMT2A
SCHEMBL8445592 0.76 KMT2A (0.54) F2PRSS1PRSS2PRSS3KMT2A
SCHEMBL13292728 0.74 F2 (0.56) F2PRSS1PRSS2PRSS3KMT2A
SCHEMBL10021501 0.74 PRSS1 (0.65) F2PRSS1PRSS2PRSS3KMT2A
SCHEMBL22310501 0.74 PRSS1 (0.65) F2PRSS1PRSS2PRSS3KMT2A
SCHEMBL3143505 0.74 PRSS1 (0.65) F2PRSS1PRSS2PRSS3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105237462-B It is a kind of that there is high flatness diamine monomer and its synthetic method and application containing carbazole structure 湖南工业大学 2018-11-27 CN disclosed
CN-105461925-B A kind of polyimides and its preparation method and application containing carbazole structure 湖南工业大学 2018-09-04 CN disclosed
CN-105482116-B A kind of polyimide nano-composite material and its preparation method and application containing carbazole structure 湖南工业大学 2018-08-07 CN disclosed
CN-105482116-A Polyimide nanometer composite with carbazole structure and preparation method and application of polyimide nanometer composite UNIV HUNAN TECH 2016-04-13 CN disclosed
CN-105461925-A Polyimide containing carbazole structure, preparation method thereof and application thereof UNIV HUNAN TECH 2016-04-06 CN disclosed
CN-105237462-A Diamine monomer containing carbazole structure and having high planarity, synthetic method and application thereof UNIV HUNAN TECHNOLOGY 2016-01-13 CN disclosed