Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049063 | 0.79 | FFAR4 (0.40) | FFAR4KDM4EXBP1ANO1PRKCZ | |
| SCHEMBL16048909 | 0.73 | FFAR4 (0.55) | FFAR4ANO1PRKCZMAPTHTT | |
| SCHEMBL28123376 | 0.70 | PTGS2 (0.40) | PTPN1NPSR1KDM4EMAPTKMT2A | |
| SCHEMBL16048409 | 0.70 | PRKCZ (0.67) | FFAR4PTPN1NPSR1KDM4EXBP1 | |
| SCHEMBL12529443 | 0.67 | PRKCZ (0.41) | EPHB4KDM4EPRKCZMAPTHTT | |
| SCHEMBL20080041 | 0.67 | FFAR4 (0.44) | FFAR4PTPN1NPSR1MAPTKMT2A | |
| SCHEMBL28049141 | 0.66 | PTGS2 (0.45) | PRKCZ | |
| SCHEMBL28049099 | 0.65 | LMNA (0.35) | FFAR4PTPN1NPSR1KDM4EPRKCZ | |
| SCHEMBL20783008 | 0.62 | FFAR4 (0.47) | FFAR4ANO1TMPRSS4 | |
| SCHEMBL4744399 | 0.61 | MIF (0.48) | NPSR1ANO1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209446-A | GPR120 agonists for the treatment of type ii diabetes | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |