Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.59 |
| ▸ | RAB9A | P51151 | 10/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244779 | 0.88 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11411034 | 0.85 | HSD17B10 (0.62) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28497934 | 0.85 | TDP1 (0.53) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28216490 | 0.82 | HSD17B10 (0.52) | RAB9ASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL366747 | 0.82 | SMN1; SMN2 (0.74) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6037493 | 0.81 | ALDH1A1 (0.75) | RAB9ASMN1; SMN2MAPTALDH1A1TDP1 | |
| SCHEMBL6037499 | 0.81 | ALDH1A1 (0.75) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27618186 | 0.81 | KIF11 (0.56) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6002669 | 0.80 | NAPRT (0.59) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6421168 | 0.80 | NAPRT (0.59) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143195-A | Furfural derivatives as a vehicle | RHODIA OPERATIONS | 2015-12-09 | — | — | CN | disclosed |