Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002669 | 0.88 | NAPRT (0.59) | NAPRTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL2244779 | 0.87 | SMN1; SMN2 (0.61) | NAPRTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL12606901 | 0.84 | NAPRT (0.55) | NAPRTHSD17B10SMN1; SMN2MAPTGAA | |
| Acetanilide SCHEMBL2652784 | 0.83 | NAPRT (0.79) | NAPRTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL28216490 | 0.82 | HSD17B10 (0.52) | NAPRTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL282531 | 0.80 | SMN1; SMN2 (0.71) | NAPRTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL15638381 | 0.80 | RAB9A (0.54) | NAPRTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL28049155 | 0.80 | NPC1 (0.59) | HSD17B10SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL23240942 | 0.79 | SMN1; SMN2 (0.52) | NAPRTHSD17B10SMN1; SMN2MAPTGAA | |
| SCHEMBL9065932 | 0.79 | SMN1; SMN2 (0.52) | NAPRTHSD17B10SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926264-B2 | Phenylcarbamate derivatives as formyl peptide receptor modulators | ALLERGAN, INC. (US) | 2018-03-27 | — | — | US | disclosed |
| EP-3071548-B1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-3071548-A1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2016-09-28 | — | — | EP | disclosed |
| US-20160272581-A1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-9431649-B2 | Coated electroactive materials | UCHICAGO ARGONNE, LLC (US) | 2016-08-30 | — | — | US | disclosed |
| WO-2015077451-A1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| US-20110121240-A1 | COATED ELECTROACTIVE MATERIALS | UCHICAGO ARGONNE, LLC | 2011-05-26 | — | — | US | disclosed |
| US-20050045064-A1 | Cellulose acylate film for optical use, and producing method thereof | FUJI PHOTO FILM CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272581-A1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | FPR2, FPR1, FPR3 | NAPRT 583/4885HSD17B10 3586/4885SMN1; SMN2 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.