Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432105 | 0.81 | POLB (0.42) | LMNA | |
| SCHEMBL28609634 | 0.81 | POLB (0.42) | LMNA | |
| SCHEMBL28049469 | 0.76 | RIPK1 (0.38) | LMNASLC6A3SLC6A2SLC6A4TP53 | |
| SCHEMBL904927 | 0.76 | CYP19A1 (0.47) | HTR7LMNASLC6A3FAAHMEN1 | |
| SCHEMBL21555834 | 0.76 | HTR7 (0.41) | HTR7SLC6A3SLC6A2DRD2DRD4 | |
| SCHEMBL27736115 | 0.75 | SLC6A2 (0.43) | SLC6A3SLC6A2SLC6A4SMN1; SMN2MMP2 | |
| SCHEMBL18503058 | 0.75 | AOC3 (0.52) | HTR7DRD2DRD3MEN1KMT2A | |
| SCHEMBL9278852 | 0.75 | HTR7 (0.40) | HTR7SLC6A3SLC6A2DRD2DRD4 | |
| SCHEMBL28015442 | 0.75 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL9232425 | 0.75 | HTR7 (0.40) | HTR7SLC6A3SLC6A2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102369188-B | As the replacement niacinamide of KCNQ2/3 conditioning agent | GRUNENTHAL GMBH (DE) | 2016-03-02 | — | — | CN | claimed |
| CN-102369188-B | As the replacement niacinamide of KCNQ2/3 conditioning agent | GRUNENTHAL GMBH (DE) | 2016-03-02 | — | — | CN | disclosed |