Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13873037 | 0.77 | RIPK1 (0.47) | RIPK1LMNA | |
| SCHEMBL28049472 | 0.76 | HTR7 (0.37) | LMNATP53SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23900862 | 0.76 | RIPK1 (0.66) | RIPK1AOC3IDO1TDO2SLC6A2 | |
| SCHEMBL22623869 | 0.74 | RIPK1 (0.67) | RIPK1AOC3SLC6A4SLC6A3 | |
| SCHEMBL28015442 | 0.73 | TRPA1 (0.41) | AOC3IDO1TDO2 | |
| SCHEMBL28049484 | 0.72 | TRPA1 (0.44) | AOC3IDO1LMNA | |
| SCHEMBL28049454 | 0.71 | FFAR1 (0.36) | RIPK1LMNATP53 | |
| SCHEMBL14007223 | 0.70 | MEN1 (0.47) | RIPK1LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14007215 | 0.66 | EPHX2 (0.56) | — | |
| SCHEMBL28049485 | 0.66 | ALDH1A1 (0.44) | AOC3IDO1LMNASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102369188-B | As the replacement niacinamide of KCNQ2/3 conditioning agent | GRUNENTHAL GMBH (DE) | 2016-03-02 | — | — | CN | claimed |
| CN-102369188-B | As the replacement niacinamide of KCNQ2/3 conditioning agent | GRUNENTHAL GMBH (DE) | 2016-03-02 | — | — | CN | disclosed |