Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232992 | 0.79 | HDAC3 (0.38) | TRPA1AOC3HTTIDO1TDO2 | |
| SCHEMBL28049484 | 0.78 | TRPA1 (0.44) | TRPA1AOC3HTTIDO1 | |
| SCHEMBL28049472 | 0.75 | HTR7 (0.37) | TRPA1 | |
| SCHEMBL28049454 | 0.73 | FFAR1 (0.36) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28049469 | 0.73 | RIPK1 (0.38) | AOC3IDO1TDO2 | |
| SCHEMBL8056888 | 0.71 | TRPA1 (0.50) | TRPA1AOC3HTTIDO1TDO2 | |
| SCHEMBL2558294 | 0.71 | TRPA1 (0.50) | TRPA1AOC3HTTIDO1TDO2 | |
| SCHEMBL2558297 | 0.71 | TRPA1 (0.50) | TRPA1AOC3HTTIDO1TDO2 | |
| SCHEMBL1772818 | 0.70 | GABBR2 (0.47) | TRPA1AOC3HTTIDO1TDO2 | |
| SCHEMBL6980610 | 0.70 | TRPA1 (0.43) | TRPA1AOC3IDO1TDO2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104780918-A | Azetidinone compound used for prevention and/or treatment of hepatitis c, and composition of compound | ZHEJIANG HISUN PHARM CO LTD | 2015-07-15 | — | — | CN | disclosed |