Phenol

Phenol

SCHEMBL28049600

Cc1ccc(F)c(Br)c1.Oc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.44
NPC1 O15118 4/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
MEN1 O00255 1/20 0.44
HSP90AA1 P07900 1/20 0.44
KMT2A Q03164 1/20 0.44
ACHE P22303 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 3/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
GLA P06280 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80216 0.84
SCHEMBL30316227 0.84
Iodide SCHEMBL28053437 0.82 NFE2L2 (0.39) RAB9ANPC1L3MBTL1MEN1HSP90AA1
Fluoride SCHEMBL27543105 0.82 NFE2L2 (0.39) RAB9ANPC1L3MBTL1MEN1HSP90AA1
Phenol SCHEMBL27884915 0.74 ALDH1A1 (0.48) NPC1ACHECYP1A2CYP2C19TDP1
SCHEMBL25339730 0.73 LMNA (0.40) RAB9ANPC1MEN1KMT2ATDP1
P-Xylene SCHEMBL599887 0.72 ACHE (0.71) RAB9ANPC1MEN1KMT2AACHE
Toluene SCHEMBL28466786 0.71 ACHE (0.52) ACHEALDH1A1HPGD
Phenol SCHEMBL27839998 0.71 ACHE (0.62) L3MBTL1MEN1KMT2AACHECYP1A2
SCHEMBL189322 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105392779-A Tetrazolinone compound and use thereof SUMITOMO CHEMICAL CO 2016-03-09 CN disclosed